The Phase Response Curve of Reciprocally Inhibitory Model Neurons Exhibiting Anti-Phase Rhythms
نویسندگان
چکیده
The phase response curve (PRC) of a half-center oscillator (HCO), which is formed by a pair of reciprocally inhibitory model neurons that exhibit anti-phase rhythms, is computed and used to identify the underlying mechanism of the HCO. The two distinct mechanisms, “release” and “escape”, give rise to two differently shaped PRCs. We use phase plane analysis to explain why the PRC is shaped differently under different mechanisms. Applying the theory of weakly coupled oscillators, we show that different mechanisms of a forced HCO can lead to different phase-lags. We also show that the distinction of the two differently shaped PRCs gets sharper as the system’s time-scales diverge more and as the synaptic activation gets faster, and that when the system is away from its relaxation regime, it is common to observe a combination of both two mechanisms.
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